Target Audience

This activity is specifically designed for clinicians, healthcare providers, and AMR stewards to address AMR at the hospital.

Learning Objectives

At the end of the module, learners should be able to:

  • Identify and describe the clinical significance, transmission routes, and virulence factors of common bacterial pathogens causing central nervous system (CNS) infections, including Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae.

  • Explain the principles of empiric versus targeted antimicrobial therapy in CNS infections, with emphasis on appropriate use of penicillin and ceftriaxone, considering CNS penetration and resistance profiles.

  • Analyze resistance mechanisms, particularly penicillin resistance in Streptococcus pneumoniae, and their implications for selecting appropriate antimicrobial therapy.

  • Apply the concept of antimicrobial breakpoints to interpret diagnostic susceptibility testing and guide rational choice of empiric and targeted antimicrobial treatment for CNS infections.

Module Outline

This module will take approximately 1 hour to complete.

  • Meningitis or Encephalitis

  • Acute CNS Presentation

  • Chronic CNS & Therapeutics

  • Recommended Readings

Course Directors

Dr. Carl Boodman, MD, FRCPC, DTM&H, CTropMed® is a Canadian infectious diseases physician, a medical microbiologist and a PhD Candidate at the Institute of Tropical Medicine/ University of Antwerp (Belgium). He is a Clinical Investigator Program Candidate at the University of Manitoba (Canada) and a member of the International Diagnostics Network.


Dr. Nitin Gupta, MBBS, MD, DM, DTM&H, CTropMed, DipRCPath, AAHIVS, PGPE, FRSPH, CIC, MTM - Associate Professor, Infectious Diseases, Kasturba Medical College, Manipal, India Coordinator, Centre for Tropical Febrile Illness, MAHE, Manipal, India.

Additional Categories

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